Index: src/where.c
==================================================================
--- src/where.c
+++ src/where.c
@@ -931,10 +931,11 @@
   if( pOrderBy ){
     int n = pOrderBy->nExpr;
     for(i=0; i<n; i++){
       Expr *pExpr = pOrderBy->a[i].pExpr;
       if( pExpr->op!=TK_COLUMN || pExpr->iTable!=pSrc->iCursor ) break;
+      if( pOrderBy->a[i].sortFlags & KEYINFO_ORDER_BIGNULL ) break;
     }
     if( i==n){
       nOrderBy = n;
     }
   }

Index: test/nulls1.test
==================================================================
--- test/nulls1.test
+++ test/nulls1.test
@@ -115,7 +115,36 @@
 } {
   200 100
   300 200
   400 300
 }
+
+#-------------------------------------------------------------------------
+ifcapable vtab {
+  register_echo_module db
+  do_execsql_test 4.0 {
+    CREATE TABLE tx(a INTEGER PRIMARY KEY, b, c);
+    CREATE INDEX i1 ON tx(b);
+    INSERT INTO tx VALUES(1, 1, 1);
+    INSERT INTO tx VALUES(2, NULL, 2);
+    INSERT INTO tx VALUES(3, 3, 3);
+    INSERT INTO tx VALUES(4, NULL, 4);
+    INSERT INTO tx VALUES(5, 5, 5);
+    CREATE VIRTUAL TABLE te USING echo(tx);
+  }
+
+  do_execsql_test 4.1 {
+    SELECT * FROM tx ORDER BY b NULLS FIRST;
+  } {2 {} 2  4 {} 4  1 1 1  3 3 3  5 5 5}
+  do_execsql_test 4.2 {
+    SELECT * FROM te ORDER BY b NULLS FIRST;
+  } {2 {} 2  4 {} 4  1 1 1  3 3 3  5 5 5}
+
+  do_execsql_test 4.3 {
+    SELECT * FROM tx ORDER BY b NULLS LAST;
+  } {1 1 1  3 3 3  5 5 5  2 {} 2  4 {} 4}
+  do_execsql_test 4.4 {
+    SELECT * FROM te ORDER BY b NULLS LAST;
+  } {1 1 1  3 3 3  5 5 5  2 {} 2  4 {} 4}
+}
 
 finish_test